Our group used bioinformatic methods and mathematical modelling to study the basic processes of life. Biological research now relies on the generation and analyses of large amounts of quantitative data, coming for example from nucleic acid sequencing and mass spectrometry. Such data need to be processed, quantified and put in context. This is done using software tools and statistics. Based on the information acquired from experiments and existing literature one can build mathematical models that can then be simulated under various conditions. The success or failure of reproducing observed behaviours tell us if we adequately understand the mechanisms of life. This activity is an important part of what is now called “systems biology”.