Knowledge base of synaptic signalling - BETA version

Glutamatergic synapses play a central role in learning and memory. Their function relies on very large transduction protein complexes coupled to downstream signalling pathways. Accurate and comprehensive knowledge of those molecular networks is key to understand the regulation of the synapse. Within the context of the EU project SynSys, we are building a knowledge repository of the signalling processes involved in the postsynaptic part of a glutamatergic synapse. Curated graphical representations of relevant signalling pathways at different levels of granularity were generated, as well as a database where information can be effectively stored and retrieved.

SynapseKB can be accessed via the minerva platform as the SynapseMap.