We are always happy to welcome new researchers in the group, whether for a few months or a few years. Based on the fundings available, we open positions dedicated to particular projects. We also host visitors who can pursue their own research interests, if relevant to our themes of research. We expect everyone to have common knowledge foundations.
Research Associate (Bioinformatics): Regenerative Cardiovascular Medicine
We are looking for a postdoctoral Research Associate to join an exciting collaboration between the groups of Dr Nicolas Le Novère (https://lenoverelab.org/) and the team of Dr Sanjay Sinha (https://www.cardiovascular.cam.ac.uk/directory/ssinha). The position is funded through the BHF Centre of Regenerative Medicine (https://www.cardiovascular.cam.ac.uk/research/oxbridgecrm), one of three national research hubs specialising in cardiovascular regeneration.
The Sinha group research is based on the hypothesis that the human epicardium contributes to heart regeneration after injury. We have pioneered the generation of epicardium from human embryonic and induced pluripotent stem cells (hESC and hiPSC) (Iyer et al., Development 2015;142:1528-41). We are using this in vitro system to understand the molecular regulation of epicardial function, and to produce cells and identify potential new drugs for regenerative medicine.
The focus of this exciting position will be to analyse data obtained from various single-cell multi-omics methods, including transcriptomics, epigenetics marks and chromatin accessibility, applied to the in vitro generated epicardium, human foetal epicardium samples and mouse or zebrafish pre- and post-infarction hearts. The successful applicant will work closely with Dr Sanjay Sinha at the Centre of Regenerative Medicine, with Dr Nicolas Le Novère at the Babraham Institute, with Professor Paul Riley (https://www.dpag.ox.ac.uk/team/paul-riley) and Professor Ludovic Vallier (https://www.cardiovascular.cam.ac.uk/directory/lvallier).
The successful applicant will have a PhD (or equivalent) with a background in bioinformatics and a publication record. Experience with the analysis of NGS data is essential, as are programming skills, in particular in R and Python. It is important that you have written and communication skills, are organised and have the ability to work collaboratively with experimental and computational colleagues.
Funding for this position is available for three years in the first instance. Starting salary is £31,604 - £38,833 per annum depending on experience.
Curator of BioModels Database
We are seeking a curator to strengthen the BioModels team. The incumbent will join our group at the Babraham Institute, as part of a collaboration with the EMBL-European Bioinformatics Institute.
The ideal candidate will be able to manage to encode, annotate, and simulate computational models of biological interest, submitted to BioModels or coming from the literature. The post holder will develop guidelines for curation, terminologies for annotation and help with the documentation and training material.
Several types of mathematical modelling techniques and software tool will be used. Relevant experience with computational models of signalling pathways, metabolic or gene networks is required to be successful in this position.
The successful candidate will have a degree in a scientific or technological field, and prior knowledge of computational systems biology. Experience with the main approaches used to model biochemical pathways, including dynamical and logical modelling, and familiarity with the main tools in the field, such as COPASI, CellDesigner, MatLab or equivalent are essential. In addition, the candidate must be an experienced Linux user.
Funding for this position is available for two years in the first instance.
Starting salary is £30,751 - £34,166 per annum depending on experience
Full details of the position can be found here. On applying please quote reference CR-NLN-BMD. Closing date for completed applications is Sunday 20th May 2018.
Fellowship-funded post-doctoral trainings
We welcome candidates who would like to undergo a post-doctoral training in the lab. If you have a good project that matches the group's interests, and a decent CV, we will assist you in writing fellowship applications. You need to have, or obtain soon, a PhD in a scientific domain. The exact field is irrelevant if you are bright and motivated. However, we expect you to have a serious knowledge of cellular and molecular biology, and feel at home with computers and mathematical modelling. Some possible sources of post-doc fellowships:
- Newton International fellowships
- EMBO Long term fellowships
- Human Frontier post-doctoral fellowships
- Marie Curie research fellowships
No funded developer positions are available at the moment.
No funded PhD positions are available at the moment.
We are always happy to host enthusiastic students for master degree internships (and sometimes bachelor, albeit only for exceptional applicants). You need to have a good knowledge of cellular and molecular biology, and solid training in basic numerical analysis. Although advanced programming skills are not required, you must be at home with computers. Geeks welcome! You'll have a desk, and access to the Babraham compute farm. We do not offer stipends. However, we support applications to various fellowships schemes.
Exchanging know-how – Visitor programme
The Babraham Institute holds extensive tacit knowledge (know-how). This knowledge is an important resource which we are keen to see shared across the scientific community. The Knowledge Exchange & Commercialisation (KEC) committee will provide funds to cover the accommodation costs of individuals (in Campus accommodation) for up to a month (~£700) to support training and knowledge exchange – applications for longer may also be considered if well justified. Travel costs will need to be found by your home laboratory. Applications (1 side of A4 with projected costs) may be sent at any time of the year.