TY - JOUR
T1 - The BioPAX community standard for pathway data sharing.
JF - Nat Biotechnol
Y1 - 2010
A1 - Demir, Emek
A1 - Cary, Michael P
A1 - Paley, Suzanne
A1 - Fukuda, Ken
A1 - Lemer, Christian
A1 - Vastrik, Imre
A1 - Wu, Guanming
A1 - D'Eustachio, Peter
A1 - Schaefer, Carl
A1 - Luciano, Joanne
A1 - Schacherer, Frank
A1 - Martinez-Flores, Irma
A1 - Hu, Zhenjun
A1 - Jimenez-Jacinto, Veronica
A1 - Joshi-Tope, Geeta
A1 - Kandasamy, Kumaran
A1 - Lopez-Fuentes, Alejandra C
A1 - Mi, Huaiyu
A1 - Pichler, Elgar
A1 - Rodchenkov, Igor
A1 - Splendiani, Andrea
A1 - Tkachev, Sasha
A1 - Zucker, Jeremy
A1 - Gopinath, Gopal
A1 - Rajasimha, Harsha
A1 - Ramakrishnan, Ranjani
A1 - Shah, Imran
A1 - Syed, Mustafa
A1 - Anwar, Nadia
A1 - Babur, Ozgün
A1 - Blinov, Michael
A1 - Brauner, Erik
A1 - Corwin, Dan
A1 - Donaldson, Sylva
A1 - Gibbons, Frank
A1 - Goldberg, Robert
A1 - Hornbeck, Peter
A1 - Luna, Augustin
A1 - Murray-Rust, Peter
A1 - Neumann, Eric
A1 - Ruebenacker, Oliver
A1 - Reubenacker, Oliver
A1 - Samwald, Matthias
A1 - van Iersel, Martijn
A1 - Wimalaratne, Sarala
A1 - Allen, Keith
A1 - Braun, Burk
A1 - Whirl-Carrillo, Michelle
A1 - Cheung, Kei-Hoi
A1 - Dahlquist, Kam
A1 - Finney, Andrew
A1 - Gillespie, Marc
A1 - Glass, Elizabeth
A1 - Gong, Li
A1 - Haw, Robin
A1 - Honig, Michael
A1 - Hubaut, Olivier
A1 - Kane, David
A1 - Krupa, Shiva
A1 - Kutmon, Martina
A1 - Leonard, Julie
A1 - Marks, Debbie
A1 - Merberg, David
A1 - Petri, Victoria
A1 - Pico, Alex
A1 - Ravenscroft, Dean
A1 - Ren, Liya
A1 - Shah, Nigam
A1 - Sunshine, Margot
A1 - Tang, Rebecca
A1 - Whaley, Ryan
A1 - Letovksy, Stan
A1 - Buetow, Kenneth H
A1 - Rzhetsky, Andrey
A1 - Schachter, Vincent
A1 - Sobral, Bruno S
A1 - Dogrusoz, Ugur
A1 - McWeeney, Shannon
A1 - Aladjem, Mirit
A1 - Birney, Ewan
A1 - Collado-Vides, Julio
A1 - Goto, Susumu
A1 - Hucka, Michael
A1 - Le Novère, Nicolas
A1 - Maltsev, Natalia
A1 - Pandey, Akhilesh
A1 - Thomas, Paul
A1 - Wingender, Edgar
A1 - Karp, Peter D
A1 - Sander, Chris
A1 - Bader, Gary D
KW - Computational Biology
KW - Databases as Topic
KW - Information Dissemination
KW - Metabolic Networks and Pathways
KW - Programming Languages
KW - Signal Transduction
KW - Software
AB - Biological Pathway Exchange (BioPAX) is a standard language to represent biological pathways at the molecular and cellular level and to facilitate the exchange of pathway data. The rapid growth of the volume of pathway data has spurred the development of databases and computational tools to aid interpretation; however, use of these data is hampered by the current fragmentation of pathway information across many databases with incompatible formats. BioPAX, which was created through a community process, solves this problem by making pathway data substantially easier to collect, index, interpret and share. BioPAX can represent metabolic and signaling pathways, molecular and genetic interactions and gene regulation networks. Using BioPAX, millions of interactions, organized into thousands of pathways, from many organisms are available from a growing number of databases. This large amount of pathway data in a computable form will support visualization, analysis and biological discovery.

VL - 28
IS - 9
U1 - http://www.ncbi.nlm.nih.gov/pubmed/20829833?dopt=Abstract
ER -