Publications

Export 196 results:
Author Title Type [ Year(Desc)]
1995
M. R. Picciotto, Zoli, M., Léna, C., Bessis, A., Lallemand, Y., Le Novère, N., Vincent, P., Pich, E. M., Brûlet, P., and Changeux, J. P., Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain., Nature, vol. 374, no. 6517, pp. 65-7, 1995.
M. Zoli, Le Novère, N., Hill, J. A., and Changeux, J. P., Developmental regulation of nicotinic ACh receptor subunit mRNAs in the rat central and peripheral nervous systems., J Neurosci, vol. 15, no. 3 Pt 1, pp. 1912-39, 1995.
N. Le Novère and Changeux, J. P., Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells., J Mol Evol, vol. 40, no. 2, pp. 155-72, 1995.
A. Bessis, Salmon, A. M., Zoli, M., Le Novère, N., Picciotto, M., and Changeux, J. P., Promoter elements conferring neuron-specific expression of the beta 2-subunit of the neuronal nicotinic acetylcholine receptor studied in vitro and in transgenic mice., Neuroscience, vol. 69, no. 3, pp. 807-19, 1995.
X. M. Li, Zoli, M., Finnman, U. B., Le Novère, N., Changeux, J. P., and Fuxe, K., A single (-)-nicotine injection causes change with a time delay in the affinity of striatal D2 receptors for antagonist, but not for agonist, nor in the D2 receptor mRNA levels in the rat substantia nigra., Brain Res, vol. 679, no. 1, pp. 157-67, 1995.
1999
C. Léna, de Kerchove D'Exaerde, A., Cordero-Erausquin, M., Le Novère, N., del Mar Arroyo-Jimenez, M., and Changeux, J. P., Diversity and distribution of nicotinic acetylcholine receptors in the locus ceruleus neurons., Proc Natl Acad Sci U S A, vol. 96, no. 21, pp. 12126-31, 1999.
N. Le Novère, Corringer, P. J., and Changeux, J. P., Improved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation., Biophys J, vol. 76, no. 5, pp. 2329-45, 1999.
R. J. Lukas, Changeux, J. P., Le Novère, N., Albuquerque, E. X., Balfour, D. J., Berg, D. K., Bertrand, D., Chiappinelli, V. A., Clarke, P. B., Collins, A. C., Dani, J. A., Grady, S. R., Kellar, K. J., Lindstrom, J. M., Marks, M. J., Quik, M., Taylor, P. W., and Wonnacott, S., International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits., Pharmacol Rev, vol. 51, no. 2, pp. 397-401, 1999.
N. Le Novère, Zoli, M., Léna, C., Ferrari, R., Picciotto, M. R., Merlo-Pich, E., and Changeux, J. P., Involvement of alpha6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion., Neuroreport, vol. 10, no. 12, pp. 2497-501, 1999.
N. Le Novère and Changeux, J. P., The Ligand Gated Ion Channel Database., Nucleic Acids Res, vol. 27, no. 1, pp. 340-2, 1999.
L. M. Marubio, del Mar Arroyo-Jimenez, M., Cordero-Erausquin, M., Léna, C., Le Novère, N., de Kerchove D'Exaerde, A., Huchet, M., Damaj, M. I., and Changeux, J. P., Reduced antinociception in mice lacking neuronal nicotinic receptor subunits., Nature, vol. 398, no. 6730, pp. 805-10, 1999.
2003
T. Grutter, Prado de Carvalho, L., Le Novère, N., Corringer, P. J., Edelstein, S., and Changeux, J. - P., An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors., EMBO J, vol. 22, no. 9, pp. 1990-2003, 2003.
N. Le Novère, La communication neuronale à l'ère post-génomique : le projet DopaNet, Biofutur, vol. 237, pp. 20-24, 2003.
Z. - Y. Han, Zoli, M., Cardona, A., Bourgeois, J. - P., Changeux, J. - P., and Le Novère, N., Localization of [3H]nicotine, [3H]cytisine, [3H]epibatidine, and [125I]alpha-bungarotoxin binding sites in the brain of Macaca mulatta., J Comp Neurol, vol. 461, no. 1, pp. 49-60, 2003.
V. Courtois, Chatelain, G., Han, Z. - Y., Le Novère, N., Brun, G., and Lamonerie, T., New Otx2 mRNA isoforms expressed in the mouse brain., J Neurochem, vol. 84, no. 4, pp. 840-53, 2003.
N. Champtiaux, Gotti, C., Cordero-Erausquin, M., David, D. J., Przybylski, C., Léna, C., Clementi, F., Moretti, M., Rossi, F. M., Le Novère, N., McIntosh, M. J., Gardier, A. M., and Changeux, J. - P., Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice., J Neurosci, vol. 23, no. 21, pp. 7820-9, 2003.
M. Hucka, Finney, A., Sauro, H. M., Bolouri, H., Doyle, J. C., Kitano, H., Arkin, A. P., Bornstein, B. J., Bray, D., Cornish-Bowden, A., Cuellar, A. A., Dronov, S., Gilles, E. D., Ginkel, M., Gor, V., Goryanin, I. I., Hedley, W. J., Hodgman, T. C., Hofmeyr, J. - H., Hunter, P. J., Juty, N. S., Kasberger, J. L., Kremling, A., Kummer, U., Le Novère, N., Loew, L. M., Lucio, D., Mendes, P., Minch, E., Mjolsness, E. D., Nakayama, Y., Nelson, M. R., Nielsen, P. F., Sakurada, T., Schaff, J. C., Shapiro, B. E., Shimizu, T. S., Spence, H. D., Stelling, J., Takahashi, K., Tomita, M., Wagner, J., and Wang, J., The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models., Bioinformatics, vol. 19, no. 4, pp. 524-31, 2003.
2006
N. Le Novère, Bornstein, B., Broicher, A., Courtot, M., Donizelli, M., Dharuri, H., Li, L., Sauro, H., Schilstra, M., Shapiro, B., Snoep, J. L., and Hucka, M., BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems., Nucleic Acids Res, vol. 34, no. Database issue, pp. D689-91, 2006.
M. J. Schilstra, Li, L., Matthews, J., Finney, A., Hucka, M., and Le Novère, N., CellML2SBML: conversion of CellML into SBML., Bioinformatics, vol. 22, no. 8, pp. 1018-20, 2006.
E. Fernandez, Schiappa, R., Girault, J. - A., and Le Novère, N., DARPP-32 is a robust integrator of dopamine and glutamate signals., PLoS Comput Biol, vol. 2, no. 12, p. e176, 2006.
M. Donizelli, Djite, M. - A., and Le Novère, N., LGICdb: a manually curated sequence database after the genomes., Nucleic Acids Res, vol. 34, no. Database issue, pp. D267-9, 2006.
N. Le Novère, Model storage, exchange and integration., BMC Neurosci, vol. 7 Suppl 1, p. S11, 2006.
A. H. V. Schapira, Bezard, E., Brotchie, J., Calon, F., Collingridge, G. L., Ferger, B., Hengerer, B., Hirsch, E., Jenner, P., Le Novère, N., Obeso, J. A., Schwarzschild, M. A., Spampinato, U., and Davidai, G., Novel pharmacological targets for the treatment of Parkinson's disease., Nat Rev Drug Discov, vol. 5, no. 10, pp. 845-54, 2006.
D. P. Tolle and Le Novère, N., Particle-based stochastic simulation in systems biology, Current Bioinformatics, vol. 1, pp. 315–320, 2006.
M. Hucka, Finney A.,, and Le Novère, N., Systems Biology Markup Language (SBML) Level 2: Structures and Facilities for Model Definitions., Nat Precedings, 2006.
2007
N. Le Novère, Courtot, M., and Laibe, C., Adding semantics in kinetics models of biochemical pathways, Proceedings of the 2nd International Symposium on experimental standard conditions of enzyme characterizations, pp. 137–153, 2007.
B. E. Shapiro, Finney, A., Hucka, M., Bornstein, B., Funahashi, A., Jouraku, A., Keating, S. M., Novère, N., Matthews, J., and Schilstra, M. J., Introduction to Systems Biology, Humana Press, 2007, pp. 395–421.
N. Le Novère, The long journey to a Systems Biology of neuronal function., BMC Syst Biol, vol. 1, p. 28, 2007.
C. Laibe and Le Novère, N., MIRIAM Resources: tools to generate and resolve robust cross-references in Systems Biology., BMC Syst Biol, vol. 1, p. 58, 2007.
B. E. Shapiro, Finney, A., Hucka, M., Borstein, B., Funahashi, A., Jouraki, A., Keating, S. M., Le Novère, N., Matthews, J. A., and Schilstra, M. J., SBML Models and MathSBML, S. Choi Humana Press, USA, 2007.
N. Rodriguez, Donizelli, M., and Le Novère, N., SBMLeditor: effective creation of models in the Systems Biology Markup language (SBML)., BMC Bioinformatics, vol. 8, p. 79, 2007.
M. Hucka, Finney, A., Hoops, S., Keating, S., and Le Novère, N., Systems biology markup language (SBML) Level 2: structures and facilities for model definitions, Nature Precedings, 2007.
N. Le Novère and Oellrich, A., Systems Biology Markup Language (SBML) Level 3 Proposal: multistate components, 2007.
2008
O. Wolkenhauer, Fell, D., De Meyts, P., Blüthgen, N., Herzel, H., Le Novère, N., Höfer, T., and van Leeuwen, I., Advancing systems biology for medical applications., ESF science policy briefing, 2008.
M. I. Stefan, Edelstein, S. J., and Le Novère, N., An allosteric model of calmodulin explains differential activation of PP2B and CaMKII., Proc Natl Acad Sci U S A, vol. 105, no. 31, pp. 10768-73, 2008.
G. Guerlet, Taly, A., Prado de Carvalho, L., Martz, A., Jiang, R., Specht, A., Le Novère, N., and Grutter, T., Comparative models of P2X2 receptor support inter-subunit ATP-binding sites., Biochem Biophys Res Commun, vol. 375, no. 3, pp. 405-9, 2008.
M. J. Herrgård, Swainston, N., Dobson, P., Dunn, W. B., Arga, Y. K., Arvas, M., Blüthgen, N., Borger, S., Costenoble, R., Heinemann, M., Hucka, M., Le Novère, N., Li, P., Liebermeister, W., Mo, M. L., Oliveira, A. P., Petranovic, D., Pettifer, S., Simeonidis, E., Smallbone, K., Spasić, I., Weichart, D., Brent, R., Broomhead, D. S., Westerhoff, H. V., Kirdar, B., Penttilä, M., Klipp, E., Palsson, B. Ø., Sauer, U., Oliver, S. G., Mendes, P., Nielsen, J., and Kell, D. B., A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology., Nat Biotechnol, vol. 26, no. 10, pp. 1155-60, 2008.
N. Le Novère, Li, L., and Girault, J. - A., DARPP-32: molecular integration of phosphorylation potential., Cell Mol Life Sci, vol. 65, no. 14, pp. 2125-7, 2008.
T. S. Shimizu and Le Novère, N., Looking inside the box: bacterial transistor arrays., Mol Microbiol, vol. 69, no. 1, pp. 5-9, 2008.
N. Le Novère, Neurological disease: are systems approaches the way forward?, Pharmacopsychiatry, vol. 41 Suppl 1, pp. S28-31, 2008.
C. F. Taylor, Field, D., Sansone, S. - A., Aerts, J., Apweiler, R., Ashburner, M., Ball, C. A., Binz, P. - A., Bogue, M., Booth, T., Brazma, A., Brinkman, R. R., Michael Clark, A., Deutsch, E. W., Fiehn, O., Fostel, J., Ghazal, P., Gibson, F., Gray, T., Grimes, G., Hancock, J. M., Hardy, N. W., Hermjakob, H., Julian, R. K., Kane, M., Kettner, C., Kinsinger, C., Kolker, E., Kuiper, M., Le Novère, N., Leebens-Mack, J., Lewis, S. E., Lord, P., Mallon, A. - M., Marthandan, N., Masuya, H., McNally, R., Mehrle, A., Morrison, N., Orchard, S., Quackenbush, J., Reecy, J. M., Robertson, D. G., Rocca-Serra, P., Rodriguez, H., Rosenfelder, H., Santoyo-Lopez, J., Scheuermann, R. H., Schober, D., Smith, B., Snape, J., Stoeckert, C. J., Tipton, K., Sterk, P., Untergasser, A., Vandesompele, J., and Wiemann, S., Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project., Nat Biotechnol, vol. 26, no. 8, pp. 889-96, 2008.
D. Köhn and Le Novere, N., SED-ML–an XML format for the implementation of the MIASE guidelines, in Proceedings of the 6th conference on Computational Methods in Systems Biology, 2008, vol. 5307, pp. 176–190.
N. Le Novère, Moodie, S., Sorokin, A., Hucka, M., Schreiber, F., Demir, E., Mi, H., Matsuoka, Y., Wegner, K., and Kitano, H., Systems biology graphical notation: process diagram level 1, 2008.
M. Hucka, Hoops, S., Keating, S., Le Novère, N., Sahle, S., and Wilkinson, D. J., Systems Biology Markup Language (SBML) Level 2: Structures and Facilities for Model Definitions, Nat Precedings, 2008.
2009
M. I. Stefan, Edelstein, S. J., and Le Novère, N., Computing phenomenologic Adair-Klotz constants from microscopic MWC parameters., BMC Syst Biol, vol. 3, p. 68, 2009.
V. Chelliah, Endler, L., Juty, N., Laibe, C., Li, C., Rodriguez, N., and Le Novère, N., Data Integration and Semantic Enrichment of Systems Biology Models and Simulations, in 6th International workshop Data Integration in the Life Sciences, 2009, vol. 5647, pp. 5–15.
L. Endler, Rodriguez, N., Juty, N., Chelliah, V., Laibe, C., Li, C., and Le Novère, N., Designing and encoding models for synthetic biology., J R Soc Interface, vol. 6 Suppl 4, pp. S405-17, 2009.
A. Dräger, Planatscher, H., Wouamba, D. M., Schröder, A., Hucka, M., Endler, L., Golebiewski, M., Müller, W., and Zell, A., Oligomeric membrane receptors: linking structural dynamics and functional kinetics, SBML2LATEX: Conversion of SBML files into human-readable reports, vol. 25, pp. 1455-1456, 2009.
A. Dräger, Planatscher, H., Wouamba, D. Motsou, Schröder, A., Hucka, M., Endler, L., Golebiewski, M., Müller, W., and Zell, A., SBML2L(A)T(E)X: conversion of SBML files into human-readable reports., Bioinformatics, vol. 25, no. 11, pp. 1455-6, 2009.
O. Wolkenhauer, Fell, D., De Meyts, P., Blüthgen, N., Herzel, H., Le Novère, N., Höfer, T., Schürrle, K., and van Leeuwen, I., SysBioMed report: advancing systems biology for medical applications., IET Syst Biol, vol. 3, no. 3, pp. 131-6, 2009.
N. Le Novère, Hucka, M., Mi, H., Moodie, S., Schreiber, F., Sorokin, A., Demir, E., Wegner, K., Aladjem, M. I., Wimalaratne, S. M., Bergman, F. T., Gauges, R., Ghazal, P., Kawaji, H., Li, L., Matsuoka, Y., Villeger, A., Boyd, S. E., Calzone, L., Courtot, M., Dogrusoz, U., Freeman, T. C., Funahashi, A., Ghosh, S., Jouraku, A., Kim, S., Kolpakov, F., Luna, A., Sahle, S., Schmidt, E., Watterson, S., Wu, G., Goryanin, I., Kell, D. B., Sander, C., Sauro, H., Snoep, J. L., Kohn, K., and Kitano, H., The Systems Biology Graphical Notation., Nat Biotechnol, vol. 27, no. 8, pp. 735-41, 2009.
H. Mi, Schreiber, F., Le Novére, N., Moodie, S., and Sorokin, A., Systems biology graphical notation: Activity flow language level 1, Nature Precedings, 2009.
N. Le Novère, Moodie, S., Sorokin, A., Schreiber, F., and Mi, H., Systems Biology Graphical Notation: Entity Relationship language Level 1, Nat Precedings, 2009.
S. Moodie, Le Novère, N., Demir, E., Mi, H., and Schreiber, F., Systems biology graphical notation: process description language level 1, Nature Precedings, 2009.
2010
C. Li, Donizelli, M., Rodriguez, N., Dharuri, H., Endler, L., Chelliah, V., Li, L., He, E., Henry, A., Stefan, M. I., Snoep, J. L., Hucka, M., Le Novère, N., and Laibe, C., BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models., BMC Syst Biol, vol. 4, p. 92, 2010.
C. Li, Courtot, M., Le Novère, N., and Laibe, C., BioModels.net Web Services, a free and integrated toolkit for computational modelling software., Brief Bioinform, vol. 11, no. 3, pp. 270-7, 2010.
E. Demir, Cary, M. P., Paley, S., Fukuda, K., Lemer, C., Vastrik, I., Wu, G., D'Eustachio, P., Schaefer, C., Luciano, J., Schacherer, F., Martinez-Flores, I., Hu, Z., Jimenez-Jacinto, V., Joshi-Tope, G., Kandasamy, K., Lopez-Fuentes, A. C., Mi, H., Pichler, E., Rodchenkov, I., Splendiani, A., Tkachev, S., Zucker, J., Gopinath, G., Rajasimha, H., Ramakrishnan, R., Shah, I., Syed, M., Anwar, N., Babur, O., Blinov, M., Brauner, E., Corwin, D., Donaldson, S., Gibbons, F., Goldberg, R., Hornbeck, P., Luna, A., Murray-Rust, P., Neumann, E., Ruebenacker, O., Reubenacker, O., Samwald, M., van Iersel, M., Wimalaratne, S., Allen, K., Braun, B., Whirl-Carrillo, M., Cheung, K. - H., Dahlquist, K., Finney, A., Gillespie, M., Glass, E., Gong, L., Haw, R., Honig, M., Hubaut, O., Kane, D., Krupa, S., Kutmon, M., Leonard, J., Marks, D., Merberg, D., Petri, V., Pico, A., Ravenscroft, D., Ren, L., Shah, N., Sunshine, M., Tang, R., Whaley, R., Letovksy, S., Buetow, K. H., Rzhetsky, A., Schachter, V., Sobral, B. S., Dogrusoz, U., McWeeney, S., Aladjem, M., Birney, E., Collado-Vides, J., Goto, S., Hucka, M., Le Novère, N., Maltsev, N., Pandey, A., Thomas, P., Wingender, E., Karp, P. D., Sander, C., and Bader, G. D., The BioPAX community standard for pathway data sharing., Nat Biotechnol, vol. 28, no. 9, pp. 935-42, 2010.
D. P. Tolle and Le Novère, N., Brownian diffusion of AMPA receptors is sufficient to explain fast onset of LTP., BMC Syst Biol, vol. 4, p. 25, 2010.
S. J. Edelstein, Stefan, M. I., and Le Novère, N., Ligand depletion in vivo modulates the dynamic range and cooperativity of signal transduction., PLoS One, vol. 5, no. 1, p. e8449, 2010.
C. Kettner, Field, D., Sansone, S., Taylor, C., Aerts, J., Binns, N., Blake, A., Britten, C. M., Marco, A., Fostel, J., Gaudet, P., González-Beltrán, A., Hardy, N., Hellemans, J., Hermjakob, H., Juty, N., Leebens-Mack, J., Maguire, E., Neumann, S., Orchard, S., Parkinson, H., Piel, W., Ranganathan, S., Rocca-Serra, P., Santarsiero, A., Shotton, D., Sterk, P., Untergasser, A., and Whetzel, P. L., Meeting Report from the Second “Minimum Information for Biological and Biomedical Investigations” (MIBBI) workshop, Standards in Genomic Sciences, vol. 3, pp. 259-266, 2010.
D. P. Tolle and Le Novère, N., Meredys, a multi-compartment reaction-diffusion simulator using multistate realistic molecular complexes., BMC Syst Biol, vol. 4, p. 24, 2010.
S. J. Edelstein and Changeux, J. - P., Oligomeric membrane receptors: linking structural dynamics and functional kinetics, Biophys J, vol. 98, pp. 2045-2052, 2010.
R. Henkel, Endler, L., Peters, A., Le Novère, N., and Waltemath, D., Ranked retrieval of Computational Biology models., BMC Bioinformatics, vol. 11, p. 423, 2010.
N. Le Novère, Realistic Models of Neurons Require Quantitative Information at the Single-cell Level, in Unravelling Single Cell Genomics, Dauphinot and Potier, Bontoux, 2010, pp. 45-53.
B. F. Baldi, Hoyer, C., and Le Novère, N., Schizophrenic: forever young?, Genome Med, vol. 2, no. 5, p. 32, 2010.
M. Hucka and Le Novère, N., Software that goes with the flow in systems biology., BMC Biol, vol. 8, p. 140, 2010.
N. Le Novère, Moodie, S., Sorokin, A., Schreiber, F., and Mi, H., Systems Biology Graphical Notation: Entity Relationship language Level 1, Nat Precedings, 2010.
S. Moodie, Le Novère, N., Demir, E., Mi, H., and Schreiber, F., Systems Biology Graphical Notation: Process Description language Level 1, Nat Precedings, 2010.
2011
J. - P. Changeux and Edelstein, S. J., Conformational selection or induced fit? 50 years of debate resolved, F1000 Biol Rep, vol. 3, p. 19, 2011.
J. - P. Changeux and Edelstein, S., Conformational selection or induced fit? 50 years of debate resolved., F1000 Biol Rep, vol. 3, p. 19, 2011.
M. Courtot, Juty, N., Knüpfer, C., Waltemath, D., Zhukova, A., Dräger, A., Dumontier, M., Finney, A., Golebiewski, M., Hastings, J., Hoops, S., Keating, S., Kell, D. B., Kerrien, S., Lawson, J., Lister, A., Lu, J., Machne, R., Mendes, P., Pocock, M., Rodriguez, N., Villeger, A., Wilkinson, D. J., Wimalaratne, S., Laibe, C., Hucka, M., and Le Novère, N., Controlled vocabularies and semantics in systems biology., Mol Syst Biol, vol. 7, p. 543, 2011.
A. Dräger, Rodriguez, N., Dumousseau, M., Dörr, A., Wrzodek, C., Le Novère, N., Zell, A., and Hucka, M., JSBML: a flexible Java library for working with SBML., Bioinformatics, vol. 27, no. 15, pp. 2167-8, 2011.
N. Le Novère, Hucka, M., Anwar, N., Bader, G. D., Demir, E., Moodie, S., and Sorokin, A., Meeting report from the first meetings of the Computational Modeling in Biology Network (COMBINE)., Stand Genomic Sci, vol. 5, no. 2, pp. 230-42, 2011.
D. Waltemath, Adams, R., Beard, D. A., Bergmann, F. T., Bhalla, U. S., Britten, R., Chelliah, V., Cooling, M. T., Cooper, J., Crampin, E. J., Garny, A., Hoops, S., Hucka, M., Hunter, P., Klipp, E., Laibe, C., Miller, A. K., Moraru, I., Nickerson, D., Nielsen, P., Nikolski, M., Sahle, S., Sauro, H. M., Schmidt, H., Snoep, J. L., Tolle, D., Wolkenhauer, O., and Le Novère, N., Minimum Information About a Simulation Experiment (MIASE)., PLoS Comput Biol, vol. 7, no. 4, p. e1001122, 2011.
D. Waltemath, Adams, R., Bergmann, F. T., Hucka, M., Kolpakov, F., Miller, A. K., Moraru, I. I., Nickerson, D., Sahle, S., Snoep, J. L., and Le Novère, N., Reproducible computational biology experiments with SED-ML--the Simulation Experiment Description Markup Language., BMC Syst Biol, vol. 5, p. 198, 2011.
M. Schulz, Krause, F., Le Novère, N., Klipp, E., and Liebermeister, W., Retrieval, alignment, and clustering of computational models based on semantic annotations., Mol Syst Biol, vol. 7, p. 512, 2011.
D. Waltemath, Swainston, N., Lister, A., Bergmann, F., Henkel, R., Hoops, S., Hucka, M., Juty, N., Keating, S., Knuepfer, C., and others, SBML Level 3 Package Proposal: Annot, Nature Precedings, 2011.
D. Waltemath, Bergmann, F. T., Adams, R., and Le Novère, N., Simulation Experiment Description Markup Language (SED-ML): Level 1 Version 1, Nat Precedings, 2011.
N. Le Novère, Demir, E., Mi, H., Moodie, S., and Villeger, A., Systems Biology Graphical Notation: Entity Relationship language Level 1 (Version 1.2), Nat Precedings, 2011.
S. Moodie, Le Novère, N., Demir, E., Mi, H., and Schreiber, F., Systems Biology Graphical Notation: Process Description language Level 1, Nat Precedings, 2011.
G. M. Dall'Olio, Marino, J., Schubert, M., Keys, K. L., Stefan, M. I., Gillespie, C. S., Poulain, P., Shameer, K., Sugar, R., Invergo, B. M., Jensen, L. J., Bertranpetit, J., and Laayouni, H., Ten Simple Rules for Getting Help from Online Scientific Communities, PLoS Computational Biology, vol. 7, p. e1002202, 2011.
2012
L. Li, Stefan, M. I., and Le Novère, N., Calcium input frequency, duration and amplitude differentially modulate the relative activation of calcineurin and CaMKII., PLoS One, vol. 7, no. 9, p. e43810, 2012.
R. Henkel, Le Novère, N., Wolkenhauer, O., and Waltemath, D., Considerations of graph-based concepts to manage of computational biology models and associated simulations, INFORMATIK 2012. 2012.
N. Juty, Le Novère, N., Hermjakob, H., and Laibe, C., Delivering “Cool URIs” that do not change, in SWAT4LS 2012, 2012.
S. M. Keating and Le Novère, N., Encoding Neuronal Models in SBML, in Computational Systems Neurobiology, N. Le Novère Springer Netherlands, 2012, pp. 459–488.
N. Juty, Le Novère, N., and Laibe, C., Identifiers.org and MIRIAM Registry: community resources to provide persistent identification., Nucleic Acids Res, vol. 40, no. Database issue, pp. D580-6, 2012.
R. R. Adams, Tsorman, N., Stratford, K., Akman, O. E., Gilmore, S., Juty, N., Le Novère, N., Millar, A. J., and Millar, A. J., The Input Signal Step Function (ISSF), a standard method to encode input signals in SBML models with software support, applied to circadian clock models., J Biol Rhythms, vol. 27, no. 4, pp. 328-32, 2012.
A. Zhukova, Adams, R., Laibe, C., and Le Novère, N., LibKiSAO: a Java library for Querying KiSAO., BMC Res Notes, vol. 5, p. 520, 2012.
M. Dumousseau, Rodriguez, N., Juty, N., and Le Novère, N., MELTING, a flexible platform to predict the melting temperatures of nucleic acids., BMC Bioinformatics, vol. 13, p. 101, 2012.
M. Mattioni, Cohen, U., and Le Novère, N., Neuronvisio: A Graphical User Interface with 3D Capabilities for NEURON., Front Neuroinform, vol. 6, p. 20, 2012.
F. Büchel, Wrzodek, C., Mittag, F., Dräger, A., Eichner, J., Rodriguez, N., Le Novère, N., and Zell, A., Qualitative translation of relations from BioPAX to SBML qual., Bioinformatics, vol. 28, no. 20, pp. 2648-53, 2012.
M. P. van Iersel, Villéger, A. C., Czauderna, T., Boyd, S. E., Bergmann, F. T., Luna, A., Demir, E., Sorokin, A., Dogrusoz, U., Matsuoka, Y., Funahashi, A., Aladjem, M. I., Mi, H., Moodie, S. L., Kitano, H., Le Novère, N., and Schreiber, F., Software support for SBGN maps: SBGN-ML and LibSBGN., Bioinformatics, vol. 28, no. 15, pp. 2016-21, 2012.
M. I. Stefan, Marshall, D. P., and Le Novère, N., Structural analysis and stochastic modelling suggest a mechanism for calmodulin trapping by CaMKII., PLoS One, vol. 7, no. 1, p. e29406, 2012.
L. Endler, Stefan, M. I., Edelstein, S. J., and Le Novère, N., Using chemical kinetics to model neuronal signalling pathways, in Computational Systems Neurobiology, N. Le Novère Springer Netherlands, 2012, pp. 81–117.
J. Hastings, Le Novere, N., Ceusters, W., Mulligan, K., and Smith, B., Wanting what we don’t want to want: Representing addiction in interoperable bio-ontologies, in Proceedings of the 3rd International Conference on Biomedical Ontology, 2012.
2013
S. J. Edelstein, Allosteric interactions after 50 years, Journal Of Molecular Biology, vol. 425, no. 9, pp. 1391–1395, 2013.
V. Chelliah, Laibe, C., and Le Novère, N., BioModels Database, A Repository of Mathematical Models of Biological Processes, in Encyclopedia of Systems Biology, Springer, 2013.
V. Chelliah, Laibe, C., and Le Novère, N., BioModels Database: a repository of mathematical models of biological processes., Methods Mol Biol, vol. 1021, pp. 189-99, 2013.
I. Thiele, Swainston, N., Fleming, R. M. T., Hoppe, A., Sahoo, S., Aurich, M. K., Haraldsdottir, H., Mo, M. L., Rolfsson, O., Stobbe, M. D., Thorleifsson, S. G., Agren, R., Bölling, C., Bordel, S., Chavali, A. K., Dobson, P., Dunn, W. B., Endler, L., Goryanin, I., Gudmundsson, S., Hala, D., Hucka, M., Hull, D., Jameson, D., Jamshidi, N., Jonsson, J. J., Juty, N., Keating, S., Nookaew, I., Le Novère, N., Malys, N., Mazein, A., Papin, J. A., Price, N. D., Selkov, E., Sigurdsson, M. I., Simeonidis, E., Sonnenschein, N., Smallbone, K., Sorokin, A., Van Beek, H., Weichart, D., Nielsen, J. B., Westerhoff, H. V., Kell, D. B., Mendes, P., and Palsson, B. Ø., A community-driven global reconstruction of human metabolism, Nat Biotechnol, vol. 31, no. 5, pp. 419-425, 2013.
A. A. Alcasabas, de Clare, M., Pir, P., and Oliver, S. G., Control analysis of the eukaryotic cell cycle using gene copy-number series in yeast tetraploids., BMC Genomics, vol. 14, p. 744, 2013.
N. Juty, Laibe, C., and Le Novère, N., Controlled annotations for systems biology., Methods Mol Biol, vol. 1021, pp. 227-45, 2013.
M. I. Stefan and Le Novère, N., Cooperative binding, PLoS Computational Biology, vol. 9, no. 6, 2013.
S. J. Edelstein and Le Novère, N., Cooperativity of allosteric receptors, Journal of Molecular Biology, vol. 425, no. 9, pp. 1424-1432, 2013.
F. Poitevin and Edelstein, S. J., Derivation of the Crick-Wyman equation for allosteric proteins defining the difference between the number of binding sites and the Hill coefficient, Journal Of Molecular Biology, vol. 425, no. 9, pp. 1497–1499, 2013.
F. Schreiber and Le Novère, N., Exchange Formats for Systems Biology: SBGN, in Encyclopedia of Systems Biology, 2013.
I. Ajmera, Swat, M., Laibe, C., Le Novère, N., and Chelliah, V., The impact of mathematical modeling on the understanding of diabetes and related complications, CPT: Pharmacometrics & Systems Pharmacology, vol. 2, p. e54, 2013.
M. Mattioni and Le Novère, N., Integration of biochemical and electrical signaling - multiscale model of the medium spiny neuron of the striatum, PLoS ONE, vol. 8, no. 7, p. e66811, 2013.
M. S. Prevost, Moraga-Cid, G., Van Renterghem, C., Edelstein, S. J., Changeux, J. - P., and Corringer, P. - J., Intermediate closed state for glycine receptor function revealed by cysteine cross-linking., Proc Natl Acad Sci U S A, vol. 110, no. 42, pp. 17113-8, 2013.
D. Waltemath, Bergmann, F. T., Chaouiya, C., Czauderna, T., Gleeson, P., Goble, C., Golebiewski, M., Hucka, M., Juty, N., Krebs, O., Le Novère, N., Mi, H., Moraru, I. I., Myers, C. J., Nickerson, D., Olivier, B. G., Rodriguez, N., Schreiber, F., Lucian, S., Zhang, F., and Eric, B., Meeting report from the fourth meeting of the Computational Modeling in Biology Network (COMBINE), Standards in Genomic Sciences, vol. 9, 2013.
K. Smallbone, Messiha, H. L., Carroll, K. M., Winder, C. L., Malys, N., Dunn, W. B., Murabito, E., Swainston, N., Dada, J. O., Khan, F., Pir, P., Simeonidis, E., Spasić, I., Wishart, J., Weichart, D., Hayes, N. W., Jameson, D., Broomhead, D. S., Oliver, S. G., Gaskell, S. J., McCarthy, J. E. G., Paton, N. W., Westerhoff, H. V., Kell, D. B., and Mendes, P., A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes., FEBS Lett, vol. 587, no. 17, pp. 2832-41, 2013.
F. Büchel, Rodriguez, N., Swainston, N., Wrzodek, C., Czauderna, T., Keller, R., Mittag, F., Schubert, M., Glont, M., Golebiewski, M., van Iersel, M., Keating, S., Rall, M., Wybrow, M., Hermjakob, H., Hucka, M., Kell, D. B., Müller, W., Mendes, P., Zell, A., Chaouiya, C., Saez-Rodriguez, J., Schreiber, F., Laibe, C., Drager, A., and Le Novère, N., Path2Models: Large-scale generation of computational models from biochemical pathway map, BMC Systems Biology, vol. 7, p. 116, 2013.
D. Waltemath, Wolkenhauer, O., Le Novère, N., and Dumontier, M., Possibilities for Integrating Model-related Data in Computational Biology, 9th International workshop Data Integration in the Life Sciences. 2013.
D. Dikicioglu, Pir, P., and Oliver, S. G., Predicting complex phenotype-genotype interactions to enable yeast engineering: Saccharomyces cerevisiae as a model organism and a cell factory., Biotechnol J, vol. 8, no. 9, pp. 1017-34, 2013.

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