LGICdb: a manually curated sequence database after the genomes.

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TitleLGICdb: a manually curated sequence database after the genomes.
Publication TypeJournal Article
Year of Publication2006
AuthorsDonizelli, M, Djite, M-A, Le Novère, N
JournalNucleic Acids Res
Volume34
IssueDatabase issue
PaginationD267-9
Date Published2006 Jan 1
ISSN1362-4962
KeywordsDatabases, Protein, Genomics, Internet, Ion Channel Gating, Ion Channels, Ligands, Protein Isoforms, Protein Subunits, Sequence Alignment, Sequence Analysis, Protein, Software, User-Computer Interface
Abstract

<p>Ligand-gated ion channels form transmembrane ionic pores controlled by the binding of chemicals. The LGICdb aims to be a non-redundant, manually curated resource offering access to the large number of subunits composing extracellularly activated ligand-gated ion channels, such as nicotinic, ATP, GABA and glutamate ionotropic receptors. Composed of more than 500 human curated entries, the XML native database has been relocated in 2004 to the EBI. Its facilities have been enhanced with a new search system, customized multiple sequence alignments and manipulation of protein structures (http://www.ebi.ac.uk/compneur-srv/LGICdb/). Despite the vast improvement of general sequence resources, the LGICdb still provide sequences unavailable elsewhere.</p>

DOI10.1093/nar/gkj104
Alternate JournalNucleic Acids Res.
PubMed ID16381861
PubMed Central IDPMC1347466