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GLUnr2bmumu  mouse glutamate receptor NMDAR2B subunit (aka ε2)

Organism Mus musculus
Date of entry creation: 28/AUG/1999 Date of last modification: 06/SEP/2002
Locus Chr 6 6 64.5 cM
General notes

From the profusion of sequences present in DDBJ|EMBL|Genbank, we can distinguish three different variants.

Sequences
transcript Note:

The NCBI prediction (XM_132919) from genomic sequences is bad, and used only in the portion when no alternative are available. elsewhere I19102 is used instead.

XM_132919:

Accession codes for other databases DDBJ|EMBL|Genbank: I19102
DDBJ|EMBL|Genbank: XM_132919
MGI: MGI:95821
  • Mishina,M. NMDH receptor proteins and genes encoding the same Patent: US 5502166-A 6 26-MAR-1996;
  • NCBI Annotation Project. Direct Submission (15-MAY-2002) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
FASTA: GLUnr2bmumu-var1.cfa EMBL: GLUnr2bmumu-var1.cem Genbank: GLUnr2bmumu-var1.cgb
transcript Note:

It is a fusion between E06594 (longer) and I19108/E06819

E06594: tissue_type=brain

E06819: tissue_type=Cerebellum

Accession codes for other databases DDBJ|EMBL|Genbank: E06594
DDBJ|EMBL|Genbank: I19108
DDBJ|EMBL|Genbank: E06819
  • Mishina,M. NOVEL PROTEIN AND GENE CODING THE SAME JOURNAL. Patent: JP 1994014783-A 1 25-JAN-1994; MITSUBISHI KASEI CORP
  • Mishina,M. NMDH receptor proteins and genes encoding the same Patent: US 5502166-A 17 26-MAR-1996;
  • Mishina,M. NEW PROTEIN AND GENE CODING THE PROTEIN. Patent: JP 1994062861-A 1 08-MAR-1994; MITSUBISHI KASEI CORP
FASTA: GLUnr2bmumu-var2.cfa EMBL: GLUnr2bmumu-var2.cem Genbank: GLUnr2bmumu-var2.cgb
transcript
Accession codes for other databases DDBJ|EMBL|Genbank: D10651
DDBJ|EMBL|Genbank: NM_008171
  • Kutsuwada,T. Direct Submission (28-FEB-1992) to the DDBJ/EMBL/GenBank databases. Tatsuya Univ. Brain Res.Inst., Dept. of Neuropharmacology; 1-757 Asahimachidori, Niigata, Niigata 951, Japan (Tel:025-223-6161(ex.5174), Fax:025-225-6458)
  • Kutsuwada,T., Kashiwabuchi,N., Mori,H., Sakimura,K., Kushiya,E., Araki,K., Meguro,H., Masaki,H., Kumanishi,T., Arakawa,M. and Mishina,M. Molecular diversity of the NMDA receptor channel. Nature 358 (6381), 36-41 (1992)
  • Kutsuwada,T. Unpublished, Sequence updated (14-Oct-1992). Department of Neuropharmacology, Brain Research Institute, Niigata University, 1-757 Asahimachidori, Niigata 951, Japan, Phone: 025-223-6161 x5147, Fax: 025-225-6458.
  • Sasner,M. and Buonanno,A. Distinct N-methyl-D-aspartate receptor 2B subunit gene sequences confer neural and developmental specific expression J. Biol. Chem. 271 (35), 21316-21322 (1996)
  • Carninci,P., Shibata,Y., Hayatsu,N., Sugahara,Y., Shibata,K., Itoh,M., Konno,H., Okazaki,Y., Muramatsu,M. and Hayashizaki,Y. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes Genome Res. 10 (10), 1617-1630 (2000)
  • Shibata,K., Itoh,M., Aizawa,K., Nagaoka,S., Sasaki,N., Carninci,P., Konno,H., Akiyama,J., Nishi,K., Kitsunai,T., Tashiro,H., Itoh,M., Sumi,N., Ishii,Y., Nakamura,S., Hazama,M., Nishine,T., Harada,A., Yamamoto,R., Matsumoto,H., Sakaguchi,S., Ikegami,T., Kashiwagi,K., Fujiwake,S., Inoue,K. and Togawa,Y. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Genome Res. 10 (11), 1757-1771 (2000)
FASTA: GLUnr2bmumu-var3.cfa EMBL: GLUnr2bmumu-var3.cem Genbank: GLUnr2bmumu-var3.cgb
protein
Accession codes for other databases DDBJ|EMBL|Genbank: D10651
DDBJ|EMBL|Genbank: NM_008171
  • Kutsuwada,T. Direct Submission (28-FEB-1992) to the DDBJ/EMBL/GenBank databases. Tatsuya Univ. Brain Res.Inst., Dept. of Neuropharmacology; 1-757 Asahimachidori, Niigata, Niigata 951, Japan (Tel:025-223-6161(ex.5174), Fax:025-225-6458)
  • Kutsuwada,T., Kashiwabuchi,N., Mori,H., Sakimura,K., Kushiya,E., Araki,K., Meguro,H., Masaki,H., Kumanishi,T., Arakawa,M. and Mishina,M. Molecular diversity of the NMDA receptor channel. Nature 358 (6381), 36-41 (1992)
  • Kutsuwada,T. Unpublished, Sequence updated (14-Oct-1992). Department of Neuropharmacology, Brain Research Institute, Niigata University, 1-757 Asahimachidori, Niigata 951, Japan, Phone: 025-223-6161 x5147, Fax: 025-225-6458.
  • Sasner,M. and Buonanno,A. Distinct N-methyl-D-aspartate receptor 2B subunit gene sequences confer neural and developmental specific expression J. Biol. Chem. 271 (35), 21316-21322 (1996)
  • Carninci,P., Shibata,Y., Hayatsu,N., Sugahara,Y., Shibata,K., Itoh,M., Konno,H., Okazaki,Y., Muramatsu,M. and Hayashizaki,Y. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes Genome Res. 10 (10), 1617-1630 (2000)
  • Shibata,K., Itoh,M., Aizawa,K., Nagaoka,S., Sasaki,N., Carninci,P., Konno,H., Akiyama,J., Nishi,K., Kitsunai,T., Tashiro,H., Itoh,M., Sumi,N., Ishii,Y., Nakamura,S., Hazama,M., Nishine,T., Harada,A., Yamamoto,R., Matsumoto,H., Sakaguchi,S., Ikegami,T., Kashiwagi,K., Fujiwake,S., Inoue,K. and Togawa,Y. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Genome Res. 10 (11), 1757-1771 (2000)
FASTA: GLUnr2bmumu-var3.pfa EMBL: GLUnr2bmumu-var3.pem Genbank: GLUnr2bmumu-var3.pgb
protein Note:

This is the isoform carrying the N589Q change. It is a fusion between E06594 (longer) and I19108/E06819 (N589Q)

E06594: tissue_type=brain

E06819: tissue_type=Cerebellum

Accession codes for other databases DDBJ|EMBL|Genbank: E06594
DDBJ|EMBL|Genbank: I19108
DDBJ|EMBL|Genbank: E06819
  • Mishina,M. NOVEL PROTEIN AND GENE CODING THE SAME JOURNAL. Patent: JP 1994014783-A 1 25-JAN-1994; MITSUBISHI KASEI CORP
  • Mishina,M. NMDH receptor proteins and genes encoding the same Patent: US 5502166-A 17 26-MAR-1996;
  • Mishina,M. NEW PROTEIN AND GENE CODING THE PROTEIN. Patent: JP 1994062861-A 1 08-MAR-1994; MITSUBISHI KASEI CORP
FASTA: GLUnr2bmumu-var2.pfa EMBL: GLUnr2bmumu-var2.pem Genbank: GLUnr2bmumu-var2.pgb
protein Note:

The NCBI prediction (XM_132919) from genomic sequences is bad, and mentioned only for references.

XM_132919:

Accession codes for other databases DDBJ|EMBL|Genbank: I19102
DDBJ|EMBL|Genbank: XM_132919
MGI: MGI:95821
  • Mishina,M. NMDH receptor proteins and genes encoding the same Patent: US 5502166-A 6 26-MAR-1996;
  • NCBI Annotation Project. Direct Submission (15-MAY-2002) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
FASTA: GLUnr2bmumu-var1.pfa EMBL: GLUnr2bmumu-var1.pem Genbank: GLUnr2bmumu-var1.pgb
Structures
Miscellanea
Phylogenetic analyses
All the information under the LGICdb format (the file is unparsable by HTML browsers. You can visualize it with the "View Source" tool of your browser.)

  Citation

Nicolas Le Novère and Jean-Pierre Changeux (1999). The Ligand-Gated Ion Channel database. Nucleic Acid Research, 27 : 340-342
( PDF version)

Last modification: Mon Jun 25 12:43:55 2007 GMT | Nicolas Le Novère

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