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ACHb2rara  rat nicotinic acetylcholine receptor β2 subunit

Organism Rattus rattus
Date of entry creation: 09/MAY/1999 Date of last modification: 19/AUG/2004
Accession codes for other databases DDBJ|EMBL|Genbank: L31622
  • Boulter,J., Connolly,J., Deneris,E.S., Goldman,D.J., Heinemann,S.F. and Patrick,J. Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family. Proc. Natl. Acad. Sci. U.S.A. 84, 7763-7767 (1987)
general notes

organism=Rattus rattus cell_type=chromaffin CDS 180. .1691

The sequences were corrected on the basis of new sequencing by Jerome Sallette. Three bases were introduced in the transcript, resulting into the change EAV to AGAL in the cytoplasmic domain. The new sequence is identical to the human one.

Sequences
transcript
FASTA: ACHb2rara.cfa EMBL: ACHb2rara.cem Genbank: ACHb2rara.cgb
protein
FASTA: ACHb2rara.pfa EMBL: ACHb2rara.pem Genbank: ACHb2rara.pgb
Structures
Model of rat (a4)2(b2)3 receptor
  • Le Nov\xE8re N., Grutter T., Changeux J.-P. (2002). Proc. Natl. Acad. Sci. USA, 99: 3210-3215.
a4b2rn.pdb: [ Download] [ View]
Model of Rat (a3)2(b2)3 receptor
  • Le Nov\xE8re N. (2002). Unpublished
a3b2rr.pdb: [ Download] [ View]
Epibatidine bound to chick Rat a3b2 binding site
  • Sallette J., Bohler S., Benoit P., Soudant M., Pons S., Le Nov\xE8re N., Changeux J.-P., Corringer P.-J. (2004) An extracellular microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. Journal of Biological Chemistry, 279: 18767-18775.
a3b2rr_epi.pdb: [ Download] [ View]
Miscellanea
Phylogenetic analyses
All the information under the LGICdb format (the file is unparsable by HTML browsers. You can visualize it with the "View Source" tool of your browser.)

  Citation

Nicolas Le Novère and Jean-Pierre Changeux (1999). The Ligand-Gated Ion Channel database. Nucleic Acid Research, 27 : 340-342
( PDF version)

Last modification: Fri Mar 17 10:35:28 2006 GMT | Nicolas Le Novère

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