ACHa5hosa  human nicotinic acetylcholine receptor α5 subunit

Organism Homo sapiens
Date of entry creation: 1999-05-02T00:00:00 Date of last modification: 2004-09-29T22:58:14
Locus Chr 15 q25.1
  • Chini,B., Clementi,F., Hukovic,N. and Sher,E. Neuronal-type alpha-bungarotoxin receptors and the alpha5-nicotinic receptor subunit gene are expressed in neuronal and nonneuronal human cell lines. Proc. Natl. Acad. Sci. U.S.A. 89 (5), 1572-1576 (1992)
  • Elliott K.J., Ellis S.B., Berckhan K.J., Urrutia A., Chavez-Noriega L.E., Johnson E.C., Velicelebi G., Harpold M.M.; "Comparative structure of human neuronal alpha2-alpha7 and beta2-beta4 nicotinic acetylcholine receptor subunits and functional expression of the alpha2, alpha3, alpha4, alpha7, beta2, and beta4 subunits."; J. Mol. Neurosci. 7:217-228(1996).
Accession codes for other databases Ensembl: ENSG00000169684
FASTA: ACHa5hosa.gfa EMBL: ACHa5hosa.gem Genbank: ACHa5hosa.ggb
transcript Note: Ensembl predicts two transcripts. However, the longest does not correspond to usual nicotinic subunits and has not been reported by cloners.
Accession codes for other databases DDBJ|EMBL|Genbank: M83712
Ensembl: ENST00000343874
FASTA: EMBL: ACHa5hosa.cem Genbank: ACHa5hosa.cgb
protein Note: The short sequence of Ensembl was chosen, based on the comparison with other mammal subunits. Note a fairly atypical amino-terminal sequence though. The sequence of Chini et al. is closer to the rat subunit in this region.
Accession codes for other databases Uniprot: ACH5_HUMAN
Ensembl: ENSP00000339373
FASTA: ACHa5hosa.pfa EMBL: ACHa5hosa.pem Genbank: ACHa5hosa.pgb
Phylogenetic analyses
All the information under the LGICdb format (the file is unparsable by HTML browsers. You can visualize it with the "View Source" tool of your browser.)


Nicolas Le Novère and Jean-Pierre Changeux (1999). The Ligand-Gated Ion Channel database. Nucleic Acid Research, 27 : 340-342
( PDF version)

Last modification: Mon Jun 25 12:42:01 2007 GMT | Nicolas Le Novère