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ACHa3rano  rat nicotinic acetylcholine receptor α3 subunit

Organism Rattus norvegicus
Date of entry creation: 1999-04-26T00:00:00 Date of last modification: 2004-11-15T21:44:59
Locus Chr 8 q24
General notes

Sequences
genomic
Accession codes for other databases Ensembl: ENSRNOG00000013829
  • Yang X., McDonough J., Fyodorov D., Morris M., Wang F., Deneris E.S.; "Characterization of an acetylcholine receptor alpha 3 gene promoter and its activation by the POU domain factor SCIP/Tst-1."; J. Biol. Chem. 269:10252-10264(1994).
FASTA: ACHa3rano.gfa EMBL: ACHa3rano.gem Genbank: ACHa3rano.ggb
transcript
Accession codes for other databases Ensembl: ENSRNOT00000019307
  • Boulter J., Evans K., Goldman D.J., Martin G., Treco D., Heinemann S.F., Patrick J.; "Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor alpha-subunit."; Nature 319:368-374(1986).
  • Boulter J., Connolly J.G., Deneris E.S., Goldman D.J., Heinemann S.F., Patrick J.; "Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family."; Proc. Natl. Acad. Sci. U.S.A. 84:7763-7767(1987).
FASTA: ACHa3rano.cfa EMBL: ACHa3rano.cem Genbank: ACHa3rano.cgb
protein Note: The proteic sequence is the Ensembl sequence prefixed by the missing MG present in the L31621 sequence
Accession codes for other databases Ensembl: ENSRNOP00000019307
UniProt: ACH3_RAT
DDBJ|EMBL|Genbank: L31621
FASTA: ACHa3rano.pfa EMBL: ACHa3rano.pem Genbank: ACHa3rano.pgb
Structures
Model of Rat (a3)2(b2)3 receptor
  • Le Novere N. (2002). Unpublished
a3b2rr.pdb: [ Download] [ View]
Epibatidine bound to chick Rat a3b2 binding site
  • Sallette J., Bohler S., Benoit P., Soudant M., Pons S., Le Novere N., Changeux J.-P., Corringer P.-J. (2004) An extracellular microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. Journal of Biological Chemistry, 279: 18767-18775.
a3b2rr_epi.pdb: [ Download] [ View]
Model of Rat (a3)2(b4)3 receptor
  • Le Novere N. (2002). Unpublished
a3b4rn.pdb: [ Download] [ View]
Miscellanea
Phylogenetic analyses
All the information under the LGICdb format (the file is unparsable by HTML browsers. You can visualize it with the "View Source" tool of your browser.)

  Citation

Nicolas Le Novère and Jean-Pierre Changeux (1999). The Ligand-Gated Ion Channel database. Nucleic Acid Research, 27 : 340-342
( PDF version)

Last modification: Mon Jun 25 12:42:00 2007 GMT | Nicolas Le Novère

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