ACHa3hosa  human nicotinic acetylcholine receptor α3 subunit

Organism Homo sapiens
Date of entry creation: 1999-04-26T00:00:00 Date of last modification: 2004-09-29T22:52:36
Accession codes for other databases Uniprot: ACH3_HUMAN
Uniprot: Q9BRR4
DDBJ|EMBL|Genbank: M37981
DDBJ|EMBL|Genbank: BC006114
OMIM: %249210
Locus Chr 15 q25.1
  • Fornasari D., Chini B., Tarroni P., Clementi F.; "Molecular cloning of human neuronal nicotinic receptor alpha 3-subunit."; Neurosci. Lett. 111:351-356(1990).
  • Mihovilovic M., Roses A.D.; "Expression of mRNAs in human thymus coding for the alpha 3 subunit of a neuronal acetylcholine receptor."; Exp. Neurol. 111:175-180(1991).
  • Elliott K.J., Ellis S.B., Berckhan K.J., Urrutia A., Chavez-Noriega L.E., Johnson E.C., Velicelebi G., Harpold M.M.; "Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits."; J. Mol. Neurosci. 7:217-228(1996).
  • Groot Kormelink P.J., Luyten W.H.M.L.; "Cloning and sequence of full-length cDNAs encoding the human neuronal nicotinic acetylcholine receptor (nAChR) subunits beta3 and beta4 and expression of seven nAChR subunits in the human neuroblastoma cell line SH-SY5Y and/or IMR-32."; FEBS Lett. 400:309-314(1997).
  • Rempel N., Heyers S., Engels H., Sleegers E., Steinlein O.K.; "The structures of the human neuronal nicotinic acetylcholine receptor beta2- and alpha3-subunit genes (CHRNB2 and CHRNA3)."; Hum. Genet. 103:645-653(1998).
  • Lev-Lehman E., Bercovich D., Xu W., Stockton D.W., Beaudet A.L.; "Characterization of the human beta4 nAChR gene and polymorphisms in CHRNA3 and CHRNB4."; J. Hum. Genet. 46:362-366(2001).
  • Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madan A., Young A.C., Shevchenko Y., Bouffard G.G., Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S.N., Krzywinski M.I., Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J.M., Marra M.A. "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."; Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002).
  • Anand R., Lindstrom J.; Submitted (JUN-1990) to the EMBL/GenBank/DDBJ databases.
  • Arredondo J., Grando S.A.; "Cloning cholinergic receptors in human keratinocytes."; Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
General notes
The transcript sequence from M37981 does not correspond to Ensembl sequence.
Accession codes for other databases Ensembl: ENSG00000080644
FASTA: ACHa3hosa.gfa EMBL: ACHa3hosa.gem Genbank: ACHa3hosa.ggb
Accession codes for other databases DDBJ|EMBL|Genbank: BC006114
FASTA: EMBL: ACHa3hosa.cem Genbank: ACHa3hosa.cgb
protein Note: Several alternative signal peptide and c-term sequence exist. This sequence is selected on the comparison with Ensembl (signal-peptide) and with other mammal sequences (c-term).
Accession codes for other databases Uniprot: Q86U77
FASTA: ACHa3hosa.pfa EMBL: ACHa3hosa.pem Genbank: ACHa3hosa.pgb
Phylogenetic analyses
All the information under the LGICdb format (the file is unparsable by HTML browsers. You can visualize it with the "View Source" tool of your browser.)


Nicolas Le Novère and Jean-Pierre Changeux (1999). The Ligand-Gated Ion Channel database. Nucleic Acid Research, 27 : 340-342
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Last modification: Mon Jun 25 12:41:59 2007 GMT | Nicolas Le Novère